Kodansha Magazine’s 20th issue which shipped today had a cover image which announces that the Cells at Work anime coming out in January 2021 will be adapting the spin off manga Cells At Work!! Code Black, which is created by  Shigemitsu Harada and Issei Hatsuyoshiya. 

The official twitter account for Cells At Work! Code Black revealed its first promotional video and visuals, with the anime set to dive into a darker tone than the original series focusing on an unhealthy body. Cells at Work! Code Black will be animated by Liden films and directed by  Hirofumi Ogura. Kenichiro Suehiro will return as the series composer while character designs will be handled by Takahiko Yoshide, ANN reported.

【TVアニメ化決定！】
「はたらく細胞BLACK」2021年1月ＴＶアニメ化決定！

ブラックな職場で奮闘する細胞たちの物語。
はたらく人たちに勇気を贈る、大人の”はたらく細胞”開幕！

働け。命ある限り——。

■公式サイトhttps://t.co/bQB0e8GvbP

■YouTubehttps://t.co/OibPaprIr0#細胞BLACK pic.twitter.com/EjhXRaPK6R

— 『はたらく細胞BLACK』【公式】 (@cellsatworkbla1) April 16, 2020

The TV anime was earlier declared to be the second season of the anime based on the original Cells at Work written by Akane Shimuzu. Season 1 of the anime had aired in July 2018 with 13 episodes. The series takes place inside the human body and focuses on a  a rookie red blood cell, AE3803, who often gets lost during deliveries, and a relentless white blood cell, U-1146, who fights against any germs that invade the body.

The cells at work manga, which was serialised in Kodansha Magazine’s Monthly Shonen Sirius has inspired several spinoff series such as Hataraku Saikin (Bacteria at Work), Hatarakanai Saibō (Cells That Don’t Work), Cells at Work! Code Black (Hataraku Saibō Black), Hataraku Saibō Friend, Hataraku Kesshōban-chan (Platelets at Work), Hataraku Saibō Baby (Cells at Work! Baby), and Hataraku Saibō Lady (Cells at Work! Lady).